ABSTRACT
Abstract Objective: To know the distribution of births of very low birth weight infants by day of the week, and whether this distribution affects the morbidity and mortality in this group of patients. Methods: This was a retrospective analysis of data collected prospectively in the Spanish SEN1500 network (2002-2011). Outborn infants, patients with major congenital anomalies, and those who died in the delivery room were excluded. Births were grouped into "weekdays" and "weekends." A multivariate logistic regression analysis was conducted to evaluate the independent effect of the birth moment on outcomes, and Cox regression for survival. Results: Out of a total of 27,205 very low birth weight infants born at and/or admitted to the participating centers, 22,961 (84.4%) met inclusion criteria. A reduction of 24% in the number of births was observed during the "weekends" compared with "weekdays". In the raw analysis, patients born on weekends exhibited higher morbidity and mortality (mortality rate: 14.2% vs. 16.5%, p < 0.001), but differences were no longer significant after adjusting for confounding factors. Conclusions: The present results suggest that current care practices reduce the proportion of births during the weekends and tend to cluster some high-risk births during this period, increasing crude morbidity and mortality. However, after adjusting for confounding factors, the differences disappear, suggesting that overall care coverage in these centers is appropriate.
Resumo Objetivo: Conhecer a distribuição dos partos de neonatos com muito baixo peso ao nascer durante a semana e se essa distribuição afeta a morbidez e a mortalidade nesse grupo de pacientes. Método: Esta é uma análise retrospectiva de dados coletados prospectivamente na rede espanhola SEN1500 (2002-2011). Foram excluídos neonatos nascidos em outro local, pacientes com grandes anomalias congênitas e pacientes falecidos na sala de parto. Os partos foram agrupados em "Dias úteis" e "Final de semana". Foi realizada uma análise de regressão logística multivariada para avaliar o efeito independente do parto sobre os resultados e uma regressão de Cox para avaliar a sobrevida. Resultados: Do total de 27.205 neonatos com muito baixo peso ao nascer nascidos e/ou internados nos centros participantes, 22.961 (84,4%) atenderam aos critérios de inclusão. Houve uma redução de 24% no número de partos no "Final de semana" em comparação com os "Dias úteis". Na análise bruta, os pacientes nascidos em finais de semana apresentaram maior morbidez e mortalidade (Taxa de mortalidade: 14,2% em comparação a 16,5%, p < 0,001), porém as diferenças não eram mais significativas após o ajuste aos fatores de confusão. Conclusões: Nossos resultados sugerem que as práticas atuais de atendimento reduzem a proporção de partos em finais de semana e tendem a agrupar alguns partos de alto risco nesse período, aumentando a morbidez e mortalidade brutas. Contudo, após o ajuste aos fatores de risco, as diferenças desaparecem, sugerindo que a cobertura de atendimento geral em nossos centros é adequada.
Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Time Factors , Infant Mortality , Morbidity , Infant, Very Low Birth Weight , Socioeconomic Factors , Brazil/epidemiology , Retrospective Studies , Risk FactorsABSTRACT
Background Air pollution has a direct influence on health. Aim To determine the association between particulate matter and contaminant gas concentrations in the environment with the number of consultations for respiratory diseases in emergency rooms in Metropolitan Santiago, Chile. Material and Methods During five years, the daily number emergency consultations for respiratory diseases and the daily concentrations of particulate matter and contaminant gases in a community of Santiago, were recorded. The degree of change of these variables during summer and winter was determined. Their correlation coefficients with a 0 to 100 days gap, were calculated. Results During winter, there was a higher number of consultations and higher pollution levels, except for O3, which increased in summer. There were positive correlations between the concentrations of different pollutants (mainly 2.5 and 10 μm particulate matter, CO and NO2). There was a negative association between consultations for respiratory diseases and O3 concentrations, an almost negligible association with SO2 and variable positive and significant associations with the concentration of other pollutants, with variations according to the time gap. Conclusions Pollution and respiratory diseases increase during winter. There are variable associations between pollutant concentrations and the number of consultations for respiratory diseases.